Advantages and disadvantages of SMANCS-Lipiodol intrahepatic arterial infusion chemotherapy for unresectable hepatocellular carcinoma

M. Suzuki, K. Fukuhara, M. Unno, K. Endoh, H. Takeuchi, H. Kodama, M. Oikawa, S. Matsuno

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Though SMANCS-Lipiodol suspension has advantages over tumor regression, its disadvantages should also be considered: (1) Anaphylactic reaction due to its high molecular weight. (2) Since it readily destroys the tissue, a smaller dose and repeated administration are required. (3) Due to its low viscosity, it easily enters the arterioles and causes damage even to the extrahepatic organs. When this drug is infused into the left hepatic artery in subsegmental fashion, it enters the neighboring gastric tissues through the communication of the left hepatic and left gastric arteries, and this ultimately causes intractable gastric ulcers. Considering the above facts, this drug should be used carefully.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume25 Suppl 1
Publication statusPublished - 1998 Feb

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Advantages and disadvantages of SMANCS-Lipiodol intrahepatic arterial infusion chemotherapy for unresectable hepatocellular carcinoma'. Together they form a unique fingerprint.

Cite this