Adult T cell leukemia accompanied by annular elastolytic giant cell granuloma

Y. Kuramoto, M. Watanabe, H. Tagami

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41 Citations (Scopus)

Abstract

We report a 74-year-old Japanese patient with adult T-cell leukemia who concurrently developed annular elastolytic giant cell granuloma. Initially, itchy granulomatous lesions developed on his face, nape of the neck and dorsa of the hands, but gradually erythematous plaques appeared on the back and lower limbs. The histology of the granulomatous lesions revealed coexistence of an epithelioid cell granuloma with giant cells that phagocytosed elastic fibres in the dermis and Pautrier's microabscesses in the overlying epidermis. Subsequent sequential histological studies of an erythematous plaque revealed the development of granulomatous changes in pre-existing lymphomatous lesions. Laboratory data revealed the presence of antibody to human T cell leukemia/lymphoma virus I and 14,200 white cells/mm3 in the peripheral blood with 2% atypical lymphocytes which eventually amounted to 30%, one month before his death.

Original languageEnglish
Pages (from-to)164-167
Number of pages4
JournalActa Dermato-Venereologica
Volume70
Issue number2
Publication statusPublished - 1990

Keywords

  • PUVA
  • etretinate

ASJC Scopus subject areas

  • Dermatology

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