Adult-onset acquired partial lipodystrophy accompanied by rheumatoid arthritis

Yusuke Muto, Taku Fujimura, Aya Kakizaki, Kenichiro Tsuchiyama, Yoshiyuki Kusakari, Setsuya Aiba

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Lipodystrophy is a group of metabolic disorders, possibly caused by autoimmune disease. In this report, we describe a case of adult-onset acquired partial lipodystrophy accompanied by rheumatoid arthritis without a family history. Interestingly, immunohistochemical staining revealed dense infiltration of IL-27-producing cells as well as MMP-7- and MMP-28-expressing cells, both of which have been reported to facilitate the development of autoimmune disease. Our present case might suggest possible mechanisms for acquired partial lipodystrophy.

Original languageEnglish
Pages (from-to)70-74
Number of pages5
JournalCase Reports in Dermatology
Volume7
Issue number1
DOIs
Publication statusPublished - 2015 May 22

Keywords

  • Acquired partial lipodystrophy
  • IL-27
  • MMP-28
  • MMP-7

ASJC Scopus subject areas

  • Dermatology

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