Adrenal Cortical Adenoma with Excess Black Pigment Deposition, Combined with Myelolipoma and Clinical Cushing's Syndrome: A Case Report and Review of the Literature

Ray Armand, Anne R. Cappola, Richard B. Horenstein, Cinthia B. Drachenberg, Hironobu Sasano, John C. Papadimitriou

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

We report a case of a functional adenoma with excess black pigment deposition and myelolipoma in the same adrenal gland in a 58-year-old woman. The patient presented with gastrointestinal bleeding, and after being diagnosed with colonic diverticulosis, underwent a total colectomy. An abdominal computerized tomographic (CT) scan during her work-up showed a right adrenal mass consistent with myelolipoma. Postoperatively, the patient was diagnosed with Cushing's syndrome and underwent a right adrenalectomy. The adrenalectomy specimen consisted of a dark brown and golden-yellow adrenal adenoma, myelolipoma, and atrophic adrenal gland. Immunostains indicated that the dark brown adenoma component was responsible for the patient's hypercortisolism. Co-occurrence of a functional black adenoma and a well-developed myelolipoma has not been reported in the literature. We describe the significant findings of this case, together with a review of the literature.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalInternational Journal of Surgical Pathology
Volume12
Issue number1
DOIs
Publication statusPublished - 2004 Jan

Keywords

  • Adrenal black adenoma
  • Adrenal gland
  • Adrenal mass
  • Cushing's syndrome
  • Myelolipoma
  • Pigmented adenoma

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

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