Adenocarcinoma in the squamous-lined esophagus without Barrett’s mucosa, probably arising from esophageal gland duct

Fumiyoshi Fujishima, Yasuhiro Nakamura, Atsuko Kasajima, Yohei Ozawa, Ken Ito, Shinji Taniuchi, Mika Watanabe, Sho Asonuma, Kaiyo Takubo, Hironobu Sasano

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Endoscopic mucosal resection (EMR) was performed for submucosal tumor (SMT)-like lesion of esophagogastric junction in an 81-year-old male. Histopathological findings revealed the presence of adenocarcinoma with high-grade cytological atypia. No foci of Barrett’s esophagus and/or heterotopic gastric mucosa were detected in the specimen. Intraepithelial squamous cell carcinoma was also not detected in the adjacent stratified squamous layer. The contour of the tumor was similar to normal esophageal gland ducts but tumor did have immunohistochemical staining patterns similar to esophageal cardiac glands. Esophageal adenocarcinoma arising in the background without the foci of Barrett’s esophagus is extremely rare and we reported the case with review of the literature in this study.

Original languageEnglish
Pages (from-to)327-331
Number of pages5
JournalEsophagus
Volume12
Issue number3
DOIs
Publication statusPublished - 2015 Jul 1

Keywords

  • Adenocarcinoma
  • Esophagus
  • Immunohistochemistry

ASJC Scopus subject areas

  • Gastroenterology

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