TY - JOUR
T1 - Adenocarcinoma at the esophageal gastric junction arising in an 11-year- old girl
AU - Sasaki, Hideyuki
AU - Sasano, Hironobu
AU - Ohi, Ryoji
AU - Imaizumi, Masue
AU - Shineha, Ryuzaburo
AU - Nakamura, Megumi
AU - Shibuya, Daisuke
AU - Hayashi, Yutaka
PY - 1999
Y1 - 1999
N2 - Gastric adenocarcinoma is one of the most common gastrointestinal (GI) malignancies, especially among Japanese adults, but represents only 0.05% of all malignant pediatric GI tumors. We report a case of gastric adenocarcinoma arising at the esophageal gastric junction of an 11-year-old girl. The tumor was polypoid, measuring 3.0 x 3.0 x 1.2 cm and was light gray and partially red in color with a stalk. Light microscopic examination of the lesion demonstrated adenocarcinoma of variable degrees of both architectural and nuclear atypia with invasion into the submucosa. Immunohistochemical findings of cytokeratin subtypes revealed positive immunoreactivity for cytokeratin subtypes 8, 19 and 20 and negative for 5/6/18, 7, 13 and 14, which is consistent with those of gastric adenocarcinoma. The patient was alive and well 12 months postoperatively.
AB - Gastric adenocarcinoma is one of the most common gastrointestinal (GI) malignancies, especially among Japanese adults, but represents only 0.05% of all malignant pediatric GI tumors. We report a case of gastric adenocarcinoma arising at the esophageal gastric junction of an 11-year-old girl. The tumor was polypoid, measuring 3.0 x 3.0 x 1.2 cm and was light gray and partially red in color with a stalk. Light microscopic examination of the lesion demonstrated adenocarcinoma of variable degrees of both architectural and nuclear atypia with invasion into the submucosa. Immunohistochemical findings of cytokeratin subtypes revealed positive immunoreactivity for cytokeratin subtypes 8, 19 and 20 and negative for 5/6/18, 7, 13 and 14, which is consistent with those of gastric adenocarcinoma. The patient was alive and well 12 months postoperatively.
KW - Childhood
KW - Cytokeratin
KW - Gastric adenocarcinoma
KW - Immunohistochemistry
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U2 - 10.1046/j.1440-1827.1999.00993.x
DO - 10.1046/j.1440-1827.1999.00993.x
M3 - Article
C2 - 10632934
AN - SCOPUS:0033497826
VL - 49
SP - 1109
EP - 1113
JO - Acta Pathologica Japonica
JF - Acta Pathologica Japonica
SN - 1320-5463
IS - 12
ER -