Addition of Antibacterial Agents to MMA-TBB Dentin Bonding Systems - Influence on Tensile Bond Strength and Antibacterial Effect-

Voshiyuki Kudou, Kenichi Obara, Toshihiro Kawashima, Minoru Kubota, Satoshi Abe, Tatsuo Endo, Masashi Komatsu, Reiichi Okuda

    Research output: Contribution to journalArticlepeer-review

    21 Citations (Scopus)

    Abstract

    To produce a bonding system which has both high bond strength and antibacterial properties, an antibacterial agent (vancomycin: VCM or metronidazol: MN) was added to the PMMA powder of 4-META/MMA-TBB resin (CB). The influence of the addition of an antibacterial agent on tensile bond strength to dentin and the antibacterial effect were investigated in this study. Forty-seven freshly extracted bovine first or second incisors were used to measure the tensile bond strength to dentin. The bond strengths to bovine dentin were not significantly decreased by addition of VCM (1%, 2%, 5%), or MN (1%) to CB (p<0.05). The antibacterial effect of CB containing antibacterial agent on six strains of bacteria was investigated by the agar plate diffusion method, analyzing the appearance of the inhibition zone around a resin disk following anaerobic culturing. The resin disks containing VCM showed antibacterial effects on all of the strains examined; the widths of the inhibition zones were 4-15 mm. The resin disks containing MN showed antibacterial effects on three strains; the widths of the inhibition zones were 0-4 mm. It was thus possible to produce a bonding system with both antibacterial effect and high tensile bond strength by addition of VCM to PMMA powder.

    Original languageEnglish
    Pages (from-to)65-74
    Number of pages10
    JournalDental materials journal
    Volume19
    Issue number1
    DOIs
    Publication statusPublished - 2000 Mar

    Keywords

    • 4-META/MMA-TBB resin
    • Antibacterial effect
    • Dentin bonding

    ASJC Scopus subject areas

    • Ceramics and Composites
    • Dentistry(all)

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