Acute renal failure due to leukemia cell infiltration followed by relapse at multiple extramedullary sites in a child with acute lymphoblastic leukemia

Atsushi Sato, Masue Imaizumi, Shuji Chikaoka, Hidetaka Niizuma, Yoshiyuki Hoshi, Junji Takeyama, Kunihiro Fujii, Toshiyuki Nishio, Mika Watanabe, Chihaya Maesawa, Yutaka Hayashi, Kazuie Iinuma

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Acute renal failure due to leukemic infiltration into the kidney is rare in childhood acute lymphoblastic leukemia (ALL). We report here a five year-old boy with ALL who presented acute renal failure caused by leukemic infiltration at onset. Treatment with predonisolone and hemodialysis was effective. However, he showed persistent or repeated relapses at extramedullary sites, such as central nervous system, testis, and pancreas, suggesting that leukemic cells of this patient may have had a high affinity to extramedullary organs. On the basis of previous reports and the experience of this patient, intensive treatment may be needed in ALL children with renal involvemet.

Original languageEnglish
Pages (from-to)825-828
Number of pages4
JournalLeukemia and Lymphoma
Volume45
Issue number4
DOIs
Publication statusPublished - 2004 Apr 1

Keywords

  • ALL
  • Acute renal failure
  • Child
  • Extramedullary relapse

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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