Acquiring toxicity of a newt, Cynops orientalis

Dietrich Mebs, Mari Yotsu-Yamashita

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)

    Abstract

    Tetrodotoxin (TTX) contents of wild-caught Chinese red-bellied newts, Cynops orientalis, and their offspring captive-reared from eggs to metamorphosed juveniles, were analysed using post-column LC-fluorescent detection (LC-FLD) and high resolution hydrophilic interaction liquid chromatography/mass spectrometry (HR-HILIC-LC/MS). TTX was detected in the parent newts and their eggs, but not in the larvae and juveniles raised under artificial condition over 20 months. However, juveniles reared in the presence of their parents, contained TTX-concentrations up to 8.05 μg/g. The origin of TTX may be implied from a close connection between the parents and their offspring.

    Original languageEnglish
    Pages (from-to)32-35
    Number of pages4
    JournalToxicon
    Volume198
    DOIs
    Publication statusPublished - 2021 Jul 30

    Keywords

    • Cynops orientalis
    • HILIC-LC/MS
    • LC-FLD
    • Newt
    • Tetrodotoxin
    • Toxin acquisition

    ASJC Scopus subject areas

    • Toxicology

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