Achitecture of porous hydroxyapatite scaffolds using polymer foam process

Zin Kook Kim, Jeong Jung Oak, Hisamichi Kimura, Takashi Goto, Akihisa Inoue, Seog Young Yoon

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Newly approach using the formation process of polymer foam is introduced in this study to prepare porous hydroxyapatite (HAp) scaffolds for bone tissue engineering applications, which could provide a better control over the microstructures of scaffolds and enhance their mechanical properties. The scaffolds prepared have an open, relatively uniform and interconnected porous structure with a pore size ranging 50 to 300 μm. A compressive strength of 5 MPa for the scaffolds with HAp content 80 wt% and higher porosity of 77% was achieved. The pore morphology and size of the scaffolds were characterized using a scanning electron microscopy. X-ray diifraction was used to determine the crystal structure. Scaffolds with desired porosity, pore size, and geometry could be prepared by using the formation process of polymer foam with controlling process parameters.

Original languageEnglish
Pages (from-to)377-383
Number of pages7
JournalJournal of Biomechanical Science and Engineering
Volume4
Issue number3
DOIs
Publication statusPublished - 2009

Keywords

  • Foaming
  • Hydroxyapatite
  • Polymer
  • Porous
  • Scaffold

ASJC Scopus subject areas

  • Biomedical Engineering

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