Condensation of racemic 3,3′-dihydroxy-4,4′-biphenanthryl [(±)-2] with (R)-1,1′-binaphthyl-2,2′-dicarboxylic acid dichloride (5) allows cyclization of only (-)-2 to give the 12-membered cyclic diester (7), the absolute configuration of which can be assigned (R,R) from steric reasons. Thus, absolute stereochemistry of (-)-2 is determined to be (R).
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry