Absence of adventitial vasa vasorum formation at the coronary segment with myocardial bridge - An optical coherence tomography study

Kensuke Nishimiya, Yasuharu Matsumoto, Hongxin Wang, Zhonglie Piao, Kazuma Ohyama, Hironori Uzuka, Kiyotaka Hao, Ryuji Tsuburaya, Jun Takahashi, Kenta Ito, Hiroaki Shimokawa

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background Myocardial bridge (MB) is a myocardial bundle through which coronary segment tunnels and could compress coronary arteries causing myocardial ischemia. However, the characteristic structural findings of MB remain to be fully elucidated. Recently, we demonstrated that optical coherence tomography (OCT) enables us to visualize adventitial vasa vasorum (VV) formation in humans. In this study, we examined adventitial VV formation at the coronary segment with MB in humans using OCT. Methods We examined 15 consecutive patients with suspected angina pectoris and MB in the left anterior descending (LAD) coronary arteries but no angiographic coronary stenosis. MB was detected on coronary angiography as a segment with milking effect. We performed intracoronary OCT imaging along the entire LAD. Morphometric analysis was performed at MB and proximal/distal segments at every 1 mm. Results OCT examination showed the absence of adventitial VV formation at MB in the LAD, while VV was clearly noted at both the proximal and distal reference segments. Adventitial VV area was significantly less at MB compared with the proximal or distal references. Conclusions These results with OCT imaging indicate that coronary segments with MB lack adventitial VV formation in humans, suggesting that MB could influence morphological and functional changes of the coronary artery.

Original languageEnglish
Pages (from-to)275-277
Number of pages3
JournalInternational Journal of Cardiology
Volume250
DOIs
Publication statusPublished - 2018 Jan 1

Keywords

  • Adventitia
  • Myocardial bridge
  • Optical coherence tomography
  • Vasa vasorum

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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