ABO-incompatible liver transplantation and patients with hepatopulmonary syndrome

Nozomi Koyamada, Susumu Satomi

Research output: Contribution to journalArticlepeer-review


From 1991 to 2000, more than 100 ABO-incompatible liver transplantations were performed in 12 institution in Japan. The overall survival rate is 60%. Survival data appear to have improved in these years even in adult cases, although acute vascular rejection causing hepatic necrosis, infection, and intrahepatic bile duct injury are major complications to be resolved. Hepatopulmonary syndrome (HPS) was considered to be a contraindication to transplantation in the 1980s. However, even severe cases can recover from hypoxia after liver transplantation, and improved survival data were reported in the 1990s. Intensive respiratory therapy after transplantation with NO inhalation allows expansion of the indications for transplantation in HPS.

Original languageEnglish
Pages (from-to)414-418
Number of pages5
JournalNippon Geka Gakkai zasshi
Issue number5
Publication statusPublished - 2002 May

ASJC Scopus subject areas

  • Medicine(all)


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