@article{9fd16d4c15064ce7a1cc83c73b32ed2f,
title = "A Visible-Light Promoted Amine Oxidation Catalyzed by a Cp*Ir Complex",
abstract = "Through a rapid screening of Cp*Ir complexes based on a turn-on type fluorescence readout, a [Cp*Ir(dipyrido[3,2-a : 2{\textquoteright},3{\textquoteright}-c]phenazine)Cl]+ complex was found to catalyze the blue-light promoted dehydrogenation of N-heterocycles under physiological conditions. In the dehydrogenation of tetrahydroisoquinolines, the catalyst preferentially yielded the monodehydrogenated product, accompanying H2O2 generation. We surmise that this mechanism may be reminiscent of flavin-dependent oxidases.",
keywords = "Biomimetic, Organometallic complex, Photocatalysis, Reaction-in-water, Selective-dehydrogenation",
author = "Davis, {Holly Jane} and Daniel H{\"a}ussinger and Ward, {Thomas R.} and Yasunori Okamoto",
note = "Funding Information: The authors acknowledge Dr. Alessandro Prescimone, Mr. Adriano d'Addio and Mr. Daniel Joss for their help with the X‐ray crystal structure analysis and NMR measurements. TRW acknowledges continued support from the Swiss National Science Foundation (grant 200020_182046), the NCCR Molecular Systems Engineering. HJD thanks the Marie Sk{\l}odowska‐Curie H2020‐MSCA‐IF‐2018 for a postdoctoral fellowship. YO thanks JST ACT−X (JPMJAX1913) and support from FRIS, Tohoku University. Funding Information: The authors acknowledge Dr. Alessandro Prescimone, Mr. Adriano d'Addio and Mr. Daniel Joss for their help with the X-ray crystal structure analysis and NMR measurements. TRW acknowledges continued support from the Swiss National Science Foundation (grant 200020_182046), the NCCR Molecular Systems Engineering. HJD thanks the Marie Sk?odowska-Curie H2020-MSCA-IF-2018 for a postdoctoral fellowship. YO thanks JST ACT?X (JPMJAX1913) and support from FRIS, Tohoku University. Publisher Copyright: {\textcopyright} 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2020",
month = sep,
day = "17",
doi = "10.1002/cctc.202000488",
language = "English",
volume = "12",
pages = "4512--4516",
journal = "ChemCatChem",
issn = "1867-3880",
publisher = "Wiley - VCH Verlag GmbH & CO. KGaA",
number = "18",
}