Abstract
Through a rapid screening of Cp*Ir complexes based on a turn-on type fluorescence readout, a [Cp*Ir(dipyrido[3,2-a : 2’,3’-c]phenazine)Cl]+ complex was found to catalyze the blue-light promoted dehydrogenation of N-heterocycles under physiological conditions. In the dehydrogenation of tetrahydroisoquinolines, the catalyst preferentially yielded the monodehydrogenated product, accompanying H2O2 generation. We surmise that this mechanism may be reminiscent of flavin-dependent oxidases.
Original language | English |
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Pages (from-to) | 4512-4516 |
Number of pages | 5 |
Journal | ChemCatChem |
Volume | 12 |
Issue number | 18 |
DOIs | |
Publication status | Published - 2020 Sep 17 |
Keywords
- Biomimetic
- Organometallic complex
- Photocatalysis
- Reaction-in-water
- Selective-dehydrogenation
ASJC Scopus subject areas
- Catalysis
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry