A synthesis of RGD model cyclic peptide by palladium-catalyzed carbonylative macrolactamization

Takayuki Doi, Seiji Kamioka, Sayaka Shimazu, Takashi Takahashi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Cyclic peptidic RGD models were efficiently synthesized by Pd(P(t-Bu) 3)2-catalyzed carbonylative macrolactamization in the presence of 4 Å molecular sieves under 10 atm of carbon monoxide.

Original languageEnglish
Pages (from-to)817-819
Number of pages3
JournalOrganic letters
Volume10
Issue number5
DOIs
Publication statusPublished - 2008 Mar 6
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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