A strategy for the synthesis of 2,3-disubstituted indoles starting from N-(o-halophenyl)allenamides

Haruhiko Fuwa, Makoto Sasaki

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

A strategy for the synthesis of 2,3-disubstituted indole derivatives based on an intramolecular carbopalladation-anion capture cascade has been developed, wherein construction of the pyrrole ring and functionalisation of the indole C2 and C3 positions were achieved by extensive use of palladium(0)-catalysed coupling reactions.

Original languageEnglish
Pages (from-to)2214-2218
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume5
Issue number14
DOIs
Publication statusPublished - 2007 Aug 2

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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