A statistical approach to the prediction of the possible presence of pollutant chemicals in the environment

Masayuki Ikeda, Akio Koizumi, Miyuki Kasahara, Takao Watanabe, Haruo Nakatsuka, Yasuyoshi Sekita

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In the present study, trials were performed to examine the applicability of Hayashi's theory of quantification (second type) to prediction of the possible presence (i.e., detection) or absence (nondetection) of a given chemical in the environment. The dependent variables employed were the results of a nationwide environmental monitoring on pollutant chemicals conducted by the Environment Agency of Japan. When 102 chemicals were analyzed utilizing five factors as independent variables-annual production, use pattern, n-octanol/water partition coefficient (P o w), water solubility, and biodegradability-it was found that production, use pattern, and P o w are the major contributing factors in the prediction. Further studies with 186 chemicals utilizing these three factors as the independent variables showed that, through the combined evaluation of the results of analyses with three pairs out of the three variables, the absence of a chemical in the environment at an analytically meaningful level can be predicted with a success rate of 94.4%. The rate for the presence was 76.4%.

Original languageEnglish
Pages (from-to)321-336
Number of pages16
JournalRegulatory Toxicology and Pharmacology
Volume7
Issue number3
DOIs
Publication statusPublished - 1987 Sep

ASJC Scopus subject areas

  • Toxicology

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