A somatic mutation of the KEAP1 gene in malignant melanoma is involved in aberrant NRF2 activation and an increase in intrinsic drug resistance

Shinpei Miura, Masahiko Shibazaki, Shuya Kasai, Shinji Yasuhira, Ayano Watanabe, Tsuyoshi Inoue, Yuich Kageshita, Kanako Tsunoda, Kazuhiro Takahashi, Toshihide Akasaka, Tomoyuki Masuda, Chihaya Maesawa

    Research output: Contribution to journalLetter

    18 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)553-556
    Number of pages4
    JournalJournal of Investigative Dermatology
    Volume134
    Issue number2
    DOIs
    Publication statusPublished - 2014 Feb

    ASJC Scopus subject areas

    • Biochemistry
    • Molecular Biology
    • Dermatology
    • Cell Biology

    Cite this

    Miura, S., Shibazaki, M., Kasai, S., Yasuhira, S., Watanabe, A., Inoue, T., Kageshita, Y., Tsunoda, K., Takahashi, K., Akasaka, T., Masuda, T., & Maesawa, C. (2014). A somatic mutation of the KEAP1 gene in malignant melanoma is involved in aberrant NRF2 activation and an increase in intrinsic drug resistance. Journal of Investigative Dermatology, 134(2), 553-556. https://doi.org/10.1038/jid.2013.343