A simple optogenetic system for behavioral analysis of freely moving small animals

Yuya Kawazoe, Hiromu Yawo, Koutarou D. Kimura

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)

    Abstract

    We present a new and simple optogenetic system for the behavioral analysis of small animals. This system includes a strong LED ring array, a high-resolution CCD camera, and the improved channelrhodopsin ChRGR. We used the system for behavioral analysis with the nematode Caenorhabditis elegans as a model, and we found that it can stimulate ChRGR expressed in the body wall muscles of the animals to modulate the behavior. Our results indicate that this system may be suitable for optogenetic behavioral analysis of freely moving small animals under various conditions to understand the principles underlying brain functions.

    Original languageEnglish
    Pages (from-to)65-68
    Number of pages4
    JournalNeuroscience Research
    Volume75
    Issue number1
    DOIs
    Publication statusPublished - 2013 Jan

    Keywords

    • Behavior
    • C. elegans
    • CCD camera
    • Channelrhodopsin
    • LED
    • Optogenetics

    ASJC Scopus subject areas

    • Neuroscience(all)

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