A Simple and High-Accuracy PID-Based Temperature Control System for Magnetic Hyperthermia Using Fiber Optic Thermometer

Akihiro Shikano, Loi Tonthat, Shin Yabukami

Research output: Contribution to journalLetterpeer-review

Abstract

Magnetic hyperthermia is very promising cancer therapy in which heating temperature is expected to be a key determinant for its success. Herein, we present a simple, real-time, and high-accuracy proportional-integral-derivative-based temperature control system for magnetic hyperthermia using widely-used induction heater and fiber optic thermometer. Our in vitro result shows that the temperature of clinically-approved Resovist® (0.5 ml) was accurately controlled with very small overshoot (e.g., 45.0 ± 0.07 °C and 55.0 ± 0.11°C for low- and high-temperature magnetic hyperthermia). Our system has the potential to be used for magnetic hyperthermia either alone or together with other cancer treatment modalities for basic and clinical studies.

Original languageEnglish
Pages (from-to)807-809
Number of pages3
JournalIEEJ Transactions on Electrical and Electronic Engineering
Volume16
Issue number5
DOIs
Publication statusPublished - 2021 May

Keywords

  • heating temperature control
  • magnetic hyperthermia
  • magnetic particles
  • PID controller
  • Resovist®

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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