A reaction product from mercuric mercury, selenite and reduced glutathione

A. Naganuma, J. Tabata, N. Imura

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Reaction of mercuric mercury and selenite in the presence of reduced glutathione (GSH) was studied. A black complex containing GSH and equimolar amounts of mercury and selenium was obtained by the reaction of sodium selenite and mercuric chloride in the presence of excess amounts of GSH. This complex was soluble in water, but insoluble in ethanol. Toxicity of the complex was very low in comparison with mercuric chloride or sodium selenite. Formation of such complex of lower toxicity in animals as described above may play an important role in the modification of toxicity of mercuric mercury by selenite.

Original languageEnglish
Pages (from-to)291-299
Number of pages9
JournalResearch Communications in Chemical Pathology and Pharmacology
Volume38
Issue number2
Publication statusPublished - 1982 Dec 1

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Toxicology
  • Pharmacology
  • Pharmacology, Toxicology and Pharmaceutics(all)

Fingerprint

Dive into the research topics of 'A reaction product from mercuric mercury, selenite and reduced glutathione'. Together they form a unique fingerprint.

Cite this