A primary tumor of mixed histological type is a novel poor prognostic factor for patients undergoing resection of liver metastasis from gastric cancer

Naoki Ikari, Kiyoaki Taniguchi, Akiko Serizawa, Takuji Yamada, Masakazu Yamamoto, Toru Furukawa

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Background: Surgical resection can be an option for the treatment of metastatic liver tumors originating from gastric cancer; however, its prognostic impact is controversial. The aim of this study was to identify prognostic factors in patients with surgical resection of liver metastasis from gastric cancer. Methods: We retrospectively analyzed the clinicopathological features of 38 consecutive patients undergoing hepatectomy for metastatic tumors from gastric cancer in our institution between 1990 and 2014. Results: The median overall survival of the patients was 28 months. The 5-year survival rate was 33.9%. Primary tumors of a mixed histological type, and residual tumors during the course of treatment were identified as significant independent poor prognostic factors. Conclusions: Histological evaluation of primary tumors may aid to identify patients suitable for undergoing surgical resection of liver metastasis from gastric cancer.

Original languageEnglish
Pages (from-to)281-288
Number of pages8
JournalJournal of Hepato-Biliary-Pancreatic Sciences
Volume24
Issue number5
DOIs
Publication statusPublished - 2017 May
Externally publishedYes

Keywords

  • Gastric cancer
  • Liver metastasis
  • Mixed histology
  • Prognostic factor
  • Surgery

ASJC Scopus subject areas

  • Medicine(all)

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