A practical and efficient method for the construction of the biphenyl framework; nucleophilic aromatic substitution on 2-methoxybenzoates with aryl grignard reagents

Tetsutaro Hattori, Takatsugu Suzuki, Sotaro Miyano

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Treatment of 2-methoxybenzoic esters derived from 2, 6-dialkylphenols with aryl Grignard reagents afforded 1,1′-biphenyl-2-carboxylates in excellent yields.

Original languageEnglish
Pages (from-to)1375-1376
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number19
DOIs
Publication statusPublished - 1991 Dec 1

ASJC Scopus subject areas

  • Molecular Medicine

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