A porous microneedle electrochemical glucose sensor fabricated on a scaffold of a polymer monolith

Research output: Contribution to journalArticlepeer-review

Abstract

Porous microneedle electrodes with pores of ∼1 µm diameter were fabricated by electroless plating of nickel followed by gold on a polymer monolith of poly(glycidyl methacrylate). The specific surface area of the fabricated electrode evaluated by the Brunauer-Emmett-Teller method was 2.559 ± 0.050 m2 g1 (standard error of mean), while that of the non-porous control was <0.001 m2 g1. Electrochemical glucose sensors were then fabricated by immobilizing glucose oxidase on the gold-plated microneedle electrodes. The sensitivity of the porous microneedle glucose sensor between 0 and 15 mM glucose was 22.99 ± 0.72 µA mM1, and that of the non-porous control was 3.16 ± 0.56 µA mM1. The amperometry of glucose concentration in solution was demonstrated using the fabricated electrode as a working electrode, along with an Ag/AgCl reference electrode and gold counter electrode both of which were made of microneedles. These results indicate the advantages of porous structures for electrochemical sensing with increased sensitivity.

Original languageEnglish
Article number024006
JournalJPhys Energy
Volume3
Issue number2
DOIs
Publication statusPublished - 2021 Apr

Keywords

  • Electrochemical sensor
  • Electroless plating
  • Glucose oxidase
  • Microneedle array
  • Porous electrode

ASJC Scopus subject areas

  • Energy(all)
  • Materials Chemistry
  • Materials Science (miscellaneous)

Fingerprint Dive into the research topics of 'A porous microneedle electrochemical glucose sensor fabricated on a scaffold of a polymer monolith'. Together they form a unique fingerprint.

Cite this