TY - JOUR
T1 - A novel translocation involving chromosomes 2, 9, 14, and 22 in chronic myeloid leukemia
AU - Endo, Kazuyasu
AU - Sato, Akiyoshi
AU - Sugawara, Tomohiro
AU - Kameoka, Junichi
AU - Fukuhara, Osamu
AU - Meguro, Kuniaki
AU - Shishido, Tomoaki
AU - Abe, Keishi
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1995/4
Y1 - 1995/4
N2 - A 46-year-old man with chronic myelogenous leukemia was found to have a new complex translocation. In chronic phase, all of the bone marrow cells had a rearrangement of a t(2;9;14;22) (p21;q34;q32;q11). Southern blot analysis of leukocyte DNA revealed rearrangement of the breakpoint cluster region (bcr) within the 5.8-Kb bcr. The patient eventually died in blast crisis 28 months later. The cytogenetic findings of bone marrow cells showed a 46,XY,t(2;9;14;22)(p21;q34;q32;qll),add(lp),del(3q) karyotype in blast crisis.
AB - A 46-year-old man with chronic myelogenous leukemia was found to have a new complex translocation. In chronic phase, all of the bone marrow cells had a rearrangement of a t(2;9;14;22) (p21;q34;q32;q11). Southern blot analysis of leukocyte DNA revealed rearrangement of the breakpoint cluster region (bcr) within the 5.8-Kb bcr. The patient eventually died in blast crisis 28 months later. The cytogenetic findings of bone marrow cells showed a 46,XY,t(2;9;14;22)(p21;q34;q32;qll),add(lp),del(3q) karyotype in blast crisis.
UR - http://www.scopus.com/inward/record.url?scp=0029032352&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029032352&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(94)00163-6
DO - 10.1016/0165-4608(94)00163-6
M3 - Article
C2 - 7736434
AN - SCOPUS:0029032352
VL - 80
SP - 155
EP - 157
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 2
ER -
