A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata

Zhi Yu Ni, Mei Dong, Bin Cong, Franoise Sauriol, Man Li Zhang, Yu Fang Wang, Chang Hong Huo, Qing Wen Shi, Hiromasa Kiyota

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Three new taxanes, 2α,9α,10β-triacetoxy-13α-(β- D-glucopyranosyloxy)taxa-4(20),11-dien-5α-ol (1), 5α,10β, 13α-triacetoxytax-11-ene-2α,7β,9α,20-tetraol (2), and 5α,10β,13β-triacetoxy-2α,7β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.

Original languageEnglish
Pages (from-to)281-283
Number of pages3
JournalPlanta Medica
Volume77
Issue number3
DOIs
Publication statusPublished - 2011 Jan 1

Keywords

  • Taxaceae
  • Taxus cuspidata
  • leaves
  • taxane glucoside
  • taxanes
  • yew

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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