A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata

Zhi Yu Ni, Mei Dong, Bin Cong, Franoise Sauriol, Man Li Zhang, Yu Fang Wang, Chang Hong Huo, Qing Wen Shi, Hiromasa Kiyota

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)

    Abstract

    Three new taxanes, 2α,9α,10β-triacetoxy-13α-(β- D-glucopyranosyloxy)taxa-4(20),11-dien-5α-ol (1), 5α,10β, 13α-triacetoxytax-11-ene-2α,7β,9α,20-tetraol (2), and 5α,10β,13β-triacetoxy-2α,7β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.

    Original languageEnglish
    Pages (from-to)281-283
    Number of pages3
    JournalPlanta Medica
    Volume77
    Issue number3
    DOIs
    Publication statusPublished - 2011 Jan 1

    Keywords

    • Taxaceae
    • Taxus cuspidata
    • leaves
    • taxane glucoside
    • taxanes
    • yew

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Molecular Medicine
    • Pharmacology
    • Pharmaceutical Science
    • Drug Discovery
    • Complementary and alternative medicine
    • Organic Chemistry

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