A novel strategy for the automated synthesis of bis-amides of 1,2- diamines

Takayuki Doi; Ichiro Hijikuro; Takashi Takahashi

doi:10.1055/s-1999-2947

A novel strategy for the automated synthesis of bis-amides of 1,2- diamines

Takayuki Doi, Ichiro Hijikuro, Takashi Takahashi

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

An automated synthesis of bis-amides from 1,2-diamines and acids was accomplished on solid-phase via selective formation of an aminoacetal of the diamine with a well-tuned polymer-supported aldehyde linker, diamidation on the polymer-supported aminoacetal, with acid-cleavage to yield product.

Original language	English
Pages (from-to)	1751-1753
Number of pages	3
Journal	Synlett
Issue number	11
DOIs	https://doi.org/10.1055/s-1999-2947
Publication status	Published - 1999 Jan 1
Externally published	Yes

Keywords

Amides
Amines
Combinatorial chemistry
Condensation
Solid-phase synthesis

ASJC Scopus subject areas

Organic Chemistry

Access to Document

10.1055/s-1999-2947

Fingerprint Dive into the research topics of 'A novel strategy for the automated synthesis of bis-amides of 1,2- diamines'. Together they form a unique fingerprint.

Cite this

@article{be390744cd504fe48998899438124bcb,

title = "A novel strategy for the automated synthesis of bis-amides of 1,2- diamines",

abstract = "An automated synthesis of bis-amides from 1,2-diamines and acids was accomplished on solid-phase via selective formation of an aminoacetal of the diamine with a well-tuned polymer-supported aldehyde linker, diamidation on the polymer-supported aminoacetal, with acid-cleavage to yield product.",

keywords = "Amides, Amines, Combinatorial chemistry, Condensation, Solid-phase synthesis",

author = "Takayuki Doi and Ichiro Hijikuro and Takashi Takahashi",

year = "1999",

month = jan,

day = "1",

doi = "10.1055/s-1999-2947",

language = "English",

pages = "1751--1753",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "11",

}

TY - JOUR

T1 - A novel strategy for the automated synthesis of bis-amides of 1,2- diamines

AU - Doi, Takayuki

AU - Hijikuro, Ichiro

AU - Takahashi, Takashi

PY - 1999/1/1

Y1 - 1999/1/1

N2 - An automated synthesis of bis-amides from 1,2-diamines and acids was accomplished on solid-phase via selective formation of an aminoacetal of the diamine with a well-tuned polymer-supported aldehyde linker, diamidation on the polymer-supported aminoacetal, with acid-cleavage to yield product.

AB - An automated synthesis of bis-amides from 1,2-diamines and acids was accomplished on solid-phase via selective formation of an aminoacetal of the diamine with a well-tuned polymer-supported aldehyde linker, diamidation on the polymer-supported aminoacetal, with acid-cleavage to yield product.

KW - Amides

KW - Amines

KW - Combinatorial chemistry

KW - Condensation

KW - Solid-phase synthesis

UR - http://www.scopus.com/inward/record.url?scp=0032705782&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032705782&partnerID=8YFLogxK

U2 - 10.1055/s-1999-2947

DO - 10.1055/s-1999-2947

M3 - Article

AN - SCOPUS:0032705782

SP - 1751

EP - 1753

JO - Synlett

JF - Synlett

SN - 0936-5214

IS - 11

ER -