A novel method of surface modification by electrochemical deoxidation: Effect on surface characteristics and initial bioactivity of zirconia

Juan Liu, Guang Hong, Yu Han Wu, Kosei Endo, Jian Min Han, Hiroyuki Kumamoto, Takeshi Wada, Hidemi Kato, Ping Gao, Keiichi Sasaki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The aim of this study was to investigate and compare the surface characteristics and initial bioactivity of ceria-stabilized zirconia/alumina nanocomposite (NANOZR) with those of yttria-stabilized zirconia (3Y-TZP) and pure titanium (CpTi) following the use of three surface modification methods; polishing, sandblasting/acid-etching (SB-E) and electrochemical deoxidation (ECD). Physical properties including surface morphology, chemical composition, X-ray diffraction, surface wettability, surface roughness, and hardness were measured. Osteoblast-like MC3T3-E1 cells were used to examine cell morphology and attachment to the surfaces of the materials. ECD treated NANOZR (NANOZR-E) showed a well-arranged, self-organized microporous surface structure with significantly low contact angles when compared with the other specimens (p < 0.05). NANOZR-E also demonstrated a slight decrease in monoclinic phase content (−4.4 wt %). The morphology and attachment of MC3T3-E1 cells on NANOZR-E were similar to those on polished and SBE-treated CpTi surfaces. Higher cell affinity was observed on NANOZR-E when compared with ECD treated 3Y-TZP. The findings of this study indicate the effectiveness of the novel technique, ECD, in the formation of a microporous surface on NANOZR when compared with both CpTi and 3Y-TZP. Moreover, this method also appears to improve the biological activity of NANOZR during the initial stage.

Original languageEnglish
Pages (from-to)2641-2652
Number of pages12
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume105
Issue number8
DOIs
Publication statusPublished - 2017 Nov

Keywords

  • MC3T3-E1
  • NANOZR
  • bioactivity
  • electrochemical deoxidation
  • surface characteristics

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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