A novel alkynylation reaction of epoxy alcohols: Use in the synthesis of erythro-6-acetoxyhexadecan-5-olide

Masahiko Yamaguchi, Ichiro Hirao

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Lithium acetylides in the presence of BF3·Et2O react with epoxy alcohols derived from (E)-allylic alcohols to give erythro-1,2-diols, a reaction used successfully in the stereoselective synthesis of erythro-hexadecan-5-olide.

Original languageEnglish
Pages (from-to)202-203
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number3
DOIs
Publication statusPublished - 1984 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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