A new synthesis of δ-lactones from oxetanes

Masahiko Yamaguchi, Keisuke Shibato, Ichiro Hirao

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


Oxetanes were reacted with lithium enolates generated from esters or amides in the presence of boron trifluoride etherate to give δ-hydroxyesters or amides in high yield, which were hydrolyzed and converted to δ-lactones.

Original languageEnglish
Pages (from-to)1159-1162
Number of pages4
JournalTetrahedron Letters
Issue number11
Publication statusPublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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