A new sarasinoside congener, sarasinoside M2, from a marine sponge collected in the Solomon Islands

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Abstract

A new sarasinoside congener (sarasinoside M2) and known sarasinoside B1 were obtained from a marine sponge. Sarasinoside M2 was suggested to have the same aglycon as sarasinoside M although the internal glucose in its sugar moiety is replaced by xylose. Sarasinosides B1 and M2 showed moderate cytotoxicity (approximate IC50 5-18 μM) toward Neuro-2a and HepG2 cell lines.

Original languageEnglish
Pages (from-to)222-225
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume81
Issue number2
DOIs
Publication statusPublished - 2017

Keywords

  • Cytotoxicity
  • MS/MS
  • Marine sponge
  • Saponin
  • Sarasinoside M

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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