A new aza-BODIPY based NIR region colorimetric and fluorescent chemodosimeter for fluoride

Bin Zou, Hui Liu, John Mack, Sisi Wang, Jiangwei Tian, Hua Lü, Zhifang Li, Zhen Shen

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)

Abstract

The synthesis and characterization of a novel NIR region fluoride sensor, that makes use of the aza-boron-dipyrromethene (aza-BODIPY) fluorophore, is described. An arylmagnesium bromide was formed by reacting 4-bromophenol with a tert-butyldimethylsilyl protecting group and magnesium, which was then used to prepare the aza-BODIPY through a reaction with phthalonitrile. The unusually strong affinity between the fluoride anion and silicon is used to create a sensor dye, which exhibits a highly specific, rapid colorimetric and 'turn-off' fluorescence response for F- in solution and in living HeLa cells. With F-, there is enhanced intramolecular charge transfer within the S1 state and this results in efficient nonradiative decay and hence in a marked decrease in fluorescence emission intensity. This journal is

Original languageEnglish
Pages (from-to)53864-53869
Number of pages6
JournalRSC Advances
Volume4
Issue number96
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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