Utilizing mice with swollen lymph nodes, we succeeded in irradiating individual metastatic lymph nodes through a hole in a lead shield. This system enabled us to increase the radiation dose to >8 Gy (the lethal dose for total-body irradiation) and evaluate both direct and abscopal antitumor effects.
- Abscopal effect
- Lymph node
- Mouse model
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging