A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

Yan Xu, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kihoon Jang, Kazuhiko Ishihara, Takehiko Kitamori

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

(Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

Original languageEnglish
Pages (from-to)3017-3021
Number of pages5
JournalAdvanced Materials
Volume22
Issue number28
DOIs
Publication statusPublished - 2010 Jul 27
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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