A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

Yan Xu; Kae Sato; Kazuma Mawatari; Tomohiro Konno; Kihoon Jang; Kazuhiko Ishihara; Takehiko Kitamori

doi:10.1002/adma.201000006

A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

Yan Xu, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kihoon Jang, Kazuhiko Ishihara, Takehiko Kitamori

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

(Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

Original language	English
Pages (from-to)	3017-3021
Number of pages	5
Journal	Advanced Materials
Volume	22
Issue number	28
DOIs	https://doi.org/10.1002/adma.201000006
Publication status	Published - 2010 Jul 27
Externally published	Yes

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201000006

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abstract = "(Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.",

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T1 - A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

AU - Xu, Yan

AU - Sato, Kae

AU - Mawatari, Kazuma

AU - Konno, Tomohiro

AU - Jang, Kihoon

AU - Ishihara, Kazuhiko

AU - Kitamori, Takehiko

PY - 2010/7/27

Y1 - 2010/7/27

N2 - (Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

AB - (Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

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A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

Abstract

ASJC Scopus subject areas

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