A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

Yan Xu; Kae Sato; Kazuma Mawatari; Tomohiro Konno; Kihoon Jang; Kazuhiko Ishihara; Takehiko Kitamori

doi:10.1002/adma.201000006

A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

Yan Xu, Kae Sato, Kazuma Mawatari, Tomohiro Konno, Kihoon Jang, Kazuhiko Ishihara, Takehiko Kitamori

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

(Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

Original language	English
Pages (from-to)	3017-3021
Number of pages	5
Journal	Advanced Materials
Volume	22
Issue number	28
DOIs	https://doi.org/10.1002/adma.201000006
Publication status	Published - 2010 Jul 27
Externally published	Yes

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

Access to Document

10.1002/adma.201000006

Fingerprint Dive into the research topics of 'A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions'. Together they form a unique fingerprint.

Cite this

@article{870dc8498095418e9b7c64b5cc943db9,

title = "A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions",

abstract = "(Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.",

author = "Yan Xu and Kae Sato and Kazuma Mawatari and Tomohiro Konno and Kihoon Jang and Kazuhiko Ishihara and Takehiko Kitamori",

year = "2010",

month = jul,

day = "27",

doi = "10.1002/adma.201000006",

language = "English",

volume = "22",

pages = "3017--3021",

journal = "Advanced Materials",

issn = "0935-9648",

publisher = "Wiley-VCH Verlag",

number = "28",

}

TY - JOUR

T1 - A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

AU - Xu, Yan

AU - Sato, Kae

AU - Mawatari, Kazuma

AU - Konno, Tomohiro

AU - Jang, Kihoon

AU - Ishihara, Kazuhiko

AU - Kitamori, Takehiko

PY - 2010/7/27

Y1 - 2010/7/27

N2 - (Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

AB - (Figure Presented) A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

UR - http://www.scopus.com/inward/record.url?scp=77954648597&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954648597&partnerID=8YFLogxK

U2 - 10.1002/adma.201000006

DO - 10.1002/adma.201000006

M3 - Article

C2 - 20503209

AN - SCOPUS:77954648597

VL - 22

SP - 3017

EP - 3021

JO - Advanced Materials

JF - Advanced Materials

SN - 0935-9648

IS - 28

ER -