A new technique for indirect measurement of microvascular pressure in normal and tumor tissue was developed, by using a microneedle which occludes the microvessels without disturbing the microcirculation system. Thus, the microvascular pressure either in normal subcutis or in tumor tissue can be measured precisely at the single vessel level. There was a considerable drop of the pressure in the smaller arterioles (less than 40 μm in diameter) in proportion to their diameters, while the pressure profile in venules was almost flat irrespective of their diameters. The mean pressure of venules 10-50 μm in diameter was 12.0 ± 5.2 cm H 2O, and some preliminary data obtained in pressure measurement of tumor vessels are also presented.
|Number of pages||6|
|Journal||Gann, The Japanese Journal of Cancer Research|
|Publication status||Published - 1983 Jun 2|
ASJC Scopus subject areas
- Cancer Research