A label-free and sensitive fluorescent method for the detection of uracil-DNA glycosylase activity

Jing Tao, Panshu Song, Yusuke Sato, Seiichi Nishizawa, Norio Teramae, Aijun Tong, Yu Xiang

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

The activity of uracil-DNA glycosylase (UDG), an enzyme in the base excision repair, is detected at a high sensitivity by a DNA substrate containing only one uracil through a label-free fluorescent approach, which is also successfully applied for the measurement of UDG inhibitors.

Original languageEnglish
Pages (from-to)929-932
Number of pages4
JournalChemical Communications
Volume51
Issue number5
DOIs
Publication statusPublished - 2015 Jan 18

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'A label-free and sensitive fluorescent method for the detection of uracil-DNA glycosylase activity'. Together they form a unique fingerprint.

Cite this