A highly enantioselective synthesis of chiral allylic alcohols by asymmetric addition of novel mixed reagents of trialkenylbismuthines/dialkylzincs to aldehydes

Itaru Sato, Noriaki Asakura, Taizo Iwashita

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19 Citations (Scopus)

Abstract

A novel mixture of reagents of trialkenylbismuthines/dialkylzincs was developed and applied toward the synthesis of chiral allylic alcohols. The chiral β-amino alcohols catalyzed addition of the mixed reagents of trialkenylbismuthines/dialkylzincs to aldehydes gave enantiomerically enriched allylic alcohols with up to 97% ee.

Original languageEnglish
Pages (from-to)2638-2642
Number of pages5
JournalTetrahedron Asymmetry
Volume18
Issue number22
DOIs
Publication statusPublished - 2007 Nov 12

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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