A heme degradation enzyme, HutZ, from Vibrio cholerae

Takeshi Uchida, Yukari Sekine, Toshitaka Matsui, Masao Ikeda-Saito, Koichiro Ishimori

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


HutZ, one of the crucial proteins of the iron uptake system in Vibrio cholerae, was purified, which binds to heme at a stoichiometry of 1:1. In the presence of ascorbic acid, the HutZ-bound heme degrades via the same intermediates observed in heme oxygenase, suggesting that HutZ works as a heme degradation enzyme.

Original languageEnglish
Pages (from-to)6741-6743
Number of pages3
JournalChemical Communications
Issue number53
Publication statusPublished - 2012 Jun 6

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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