A guide to facilitate the early treatment of patients with idiopathic demyelinating disease (multiple sclerosis and neuromyelitis optica)

W. M. Carroll, T. Saida, H. J. Kim, J. Kira, A. G. Kermode, C. P. Tsai, K. Fujihara, S. Kusunoki, M. Tanaka, K. K. Kim, D. Bates

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Abstract

Definite diagnosis of inflammatory demyelinating disease (multiple sclerosis (MS) and neuromyelitis optica (NMO)) may require time, but early treatment offers the opportunity to maximize patient outcomes. The purpose of this report is to provide guidance to facilitate early treatment decisions for patients with inflammatory demyelinating disease, before definitive diagnosis. Neurology experts reviewed the existing literature and clinical evidence. A treatment decision pathway was developed, defining patients for whom first-line MS disease-modifying therapies (a) are unlikely to be effective, (b) may be effective but require careful monitoring and (c) are likely to provide benefit. This algorithm seeks to ensure that patients, particularly those in Asia, receive appropriate treatment early in inflammatory demyelinating disease.

Original languageEnglish
Pages (from-to)1371-1380
Number of pages10
JournalMultiple Sclerosis Journal
Volume19
Issue number10
DOIs
Publication statusPublished - 2013 Sep

Keywords

  • Asia
  • Multiple sclerosis
  • diagnosis
  • interferon beta
  • neuromyelitis optica

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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    Carroll, W. M., Saida, T., Kim, H. J., Kira, J., Kermode, A. G., Tsai, C. P., Fujihara, K., Kusunoki, S., Tanaka, M., Kim, K. K., & Bates, D. (2013). A guide to facilitate the early treatment of patients with idiopathic demyelinating disease (multiple sclerosis and neuromyelitis optica). Multiple Sclerosis Journal, 19(10), 1371-1380. https://doi.org/10.1177/1352458512471092