A General Route to the Synthesis of N-Protected 1-Substituted and 1,2-Disubstituted Taurines

Jiaxi Xu, Shu Xu

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

N-Benzyloxycarbonyl protected α-substituted and αβ- disubstituted taurines were synthesized from olefins and epoxides via N-benzyloxycarbonylamino alcohol thioacetates as key intermediates. They are important sulfur analogues of naturally occurring amino acids and building blocks for the synthesis of α-substituted and α,β- disubstituted β-sulfonopeptides.

Original languageEnglish
Pages (from-to)276-282
Number of pages7
JournalSynthesis
Issue number2
DOIs
Publication statusPublished - 2004 Feb 2
Externally publishedYes

Keywords

  • Amino acid
  • Aminoalkanesulfonic acid
  • Epoxide
  • Olefin
  • Synthesis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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