A General Route to the Synthesis of N-Protected 1-Substituted and 1,2-Disubstituted Taurines

Jiaxi Xu, Shu Xu

    Research output: Contribution to journalArticle

    38 Citations (Scopus)

    Abstract

    N-Benzyloxycarbonyl protected α-substituted and αβ- disubstituted taurines were synthesized from olefins and epoxides via N-benzyloxycarbonylamino alcohol thioacetates as key intermediates. They are important sulfur analogues of naturally occurring amino acids and building blocks for the synthesis of α-substituted and α,β- disubstituted β-sulfonopeptides.

    Original languageEnglish
    Pages (from-to)276-282
    Number of pages7
    JournalSynthesis
    Issue number2
    DOIs
    Publication statusPublished - 2004 Feb 2

    Keywords

    • Amino acid
    • Aminoalkanesulfonic acid
    • Epoxide
    • Olefin
    • Synthesis

    ASJC Scopus subject areas

    • Catalysis
    • Organic Chemistry

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