A General Route to the Synthesis of N-Protected 1-Substituted and 1,2-Disubstituted Taurines

Jiaxi Xu; Shu Xu

doi:10.1055/s-2003-44382

A General Route to the Synthesis of N-Protected 1-Substituted and 1,2-Disubstituted Taurines

Jiaxi Xu, Shu Xu

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

N-Benzyloxycarbonyl protected α-substituted and αβ- disubstituted taurines were synthesized from olefins and epoxides via N-benzyloxycarbonylamino alcohol thioacetates as key intermediates. They are important sulfur analogues of naturally occurring amino acids and building blocks for the synthesis of α-substituted and α,β- disubstituted β-sulfonopeptides.

Original language	English
Pages (from-to)	276-282
Number of pages	7
Journal	Synthesis
Issue number	2
DOIs	https://doi.org/10.1055/s-2003-44382
Publication status	Published - 2004 Feb 2

Keywords

Amino acid
Aminoalkanesulfonic acid
Epoxide
Olefin
Synthesis

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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N2 - N-Benzyloxycarbonyl protected α-substituted and αβ- disubstituted taurines were synthesized from olefins and epoxides via N-benzyloxycarbonylamino alcohol thioacetates as key intermediates. They are important sulfur analogues of naturally occurring amino acids and building blocks for the synthesis of α-substituted and α,β- disubstituted β-sulfonopeptides.

AB - N-Benzyloxycarbonyl protected α-substituted and αβ- disubstituted taurines were synthesized from olefins and epoxides via N-benzyloxycarbonylamino alcohol thioacetates as key intermediates. They are important sulfur analogues of naturally occurring amino acids and building blocks for the synthesis of α-substituted and α,β- disubstituted β-sulfonopeptides.

KW - Amino acid

KW - Aminoalkanesulfonic acid

KW - Epoxide

KW - Olefin

KW - Synthesis

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A General Route to the Synthesis of N-Protected 1-Substituted and 1,2-Disubstituted Taurines

Abstract

Keywords

ASJC Scopus subject areas

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