Abstract
(matrix presented) A general method for convergent assembly of polyether structure has been developed based on palladium(0)-mediated Suzuki cross-coupling reaction of alkylboranes with cyclic ketene acetal phosphates. The present method allowed for coupling of medium-sized ether rings and thus a concise synthesis of the ABCD ring system of ciguatoxins has been achieved.
| Original language | English |
|---|---|
| Pages (from-to) | 1075-1077 |
| Number of pages | 3 |
| Journal | Organic letters |
| Volume | 1 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1999 Oct 7 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Sasaki, M., Fuwa, H., Ishikawa, M., & Tachibana, K. (1999). A general method for convergent synthesis of polycyclic ethers based on Suzuki cross-coupling: Concise synthesis of the ABCD ring system of ciguatoxin. Organic letters, 1(7), 1075-1077. https://doi.org/10.1021/ol990885n