TY - GEN
T1 - A fast retrieval of DNA sequences using histogram information
AU - Chen, Qiu
AU - Kotani, Koji
AU - Lee, Feifei
AU - Ohmi, Tadahiro
PY - 2009/12/1
Y1 - 2009/12/1
N2 - DNA sequence retrieval is a very important topic in bioinformatics algorithm development. However, this task usually spends much computational time to search on large DNA sequence database. This paper presents an efficient hierarchical method to improve the search speed while the accurate is being kept constant. For a given query sequence, firstly, a fast histogram method is used to scan the sequences in the database. A large number of DNA sequences with low similarity will be excluded for latter searching. The Smith-Waterman algorithm is then applied to each remainder sequences. Experimental results show the proposed method combining histogram information and Smith-Waterman algorithm is a more efficient algorithm for DNA sequence retrieval.
AB - DNA sequence retrieval is a very important topic in bioinformatics algorithm development. However, this task usually spends much computational time to search on large DNA sequence database. This paper presents an efficient hierarchical method to improve the search speed while the accurate is being kept constant. For a given query sequence, firstly, a fast histogram method is used to scan the sequences in the database. A large number of DNA sequences with low similarity will be excluded for latter searching. The Smith-Waterman algorithm is then applied to each remainder sequences. Experimental results show the proposed method combining histogram information and Smith-Waterman algorithm is a more efficient algorithm for DNA sequence retrieval.
KW - DNA sequence
KW - Fast retrieval
KW - Histogram information
KW - Smith-Waterman algorithm
UR - http://www.scopus.com/inward/record.url?scp=77950869833&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950869833&partnerID=8YFLogxK
U2 - 10.1109/FITME.2009.137
DO - 10.1109/FITME.2009.137
M3 - Conference contribution
AN - SCOPUS:77950869833
SN - 9780769538808
T3 - 2009 2nd International Conference on Future Information Technology and Management Engineering, FITME 2009
SP - 529
EP - 532
BT - 2009 2nd International Conference on Future Information Technology and Management Engineering, FITME 2009
T2 - 2009 2nd International Conference on Future Information Technology and Management Engineering, FITME 2009
Y2 - 13 December 2009 through 14 December 2009
ER -