The α-selective effect and potency of AgPF6 on readily prepared 2-deoxythioglycosides allows the direct attachment of a partially protected allo-sugar, such as L-mycarose, to an advanced and hindered aglycon unit of kedarcidin (see picture). This method also permits access to other 2-deoxyglycosides in an expedient and mild manager. PMBM = p-methoxybenzyloxymethyl, Alloc = allyloxycarbonyl, TES = triethlsilyl.
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - 2001 Mar 2|
- Deoxy sugars
- Silver hexafluorophosphate
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