A concise enantioselective synthesis of (+)-muscarine from (R)-O-benzylglycidol [(R)-benzyloxymethyloxirane]

Seiichi Takano; Yoshiharu Iwabuchi; Kunio Ogasawara

doi:10.1039/C39890001371

A concise enantioselective synthesis of (+)-muscarine from (R)-O-benzylglycidol [(R)-benzyloxymethyloxirane]

Seiichi Takano, Yoshiharu Iwabuchi, Kunio Ogasawara

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

A concise enantioselective synthesis of (+)-muscarine has been established via the novel formation of a 3,4-dihydrofuran starting from (R)-O- benzylglycidol.

Original language	English
Pages (from-to)	1371-1372
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	18
DOIs	https://doi.org/10.1039/C39890001371
Publication status	Published - 1989 Jan 1

ASJC Scopus subject areas

Molecular Medicine

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title = "A concise enantioselective synthesis of (+)-muscarine from (R)-O-benzylglycidol [(R)-benzyloxymethyloxirane]",

abstract = "A concise enantioselective synthesis of (+)-muscarine has been established via the novel formation of a 3,4-dihydrofuran starting from (R)-O- benzylglycidol.",

author = "Seiichi Takano and Yoshiharu Iwabuchi and Kunio Ogasawara",

year = "1989",

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doi = "10.1039/C39890001371",

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AU - Ogasawara, Kunio

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