TY - JOUR
T1 - A compensatory mechanism in unilateral akinetic-rigid syndrome
T2 - An fMRI study
AU - Kinomoto, Keiko
AU - Takayama, Yoshihro
AU - Abe, Mitsunari
AU - Nakamura, Kimihiro
AU - Akiguchi, Ichiro
PY - 2004/9/1
Y1 - 2004/9/1
N2 - The motor mechanisms of a patient with unilateral hand clumsiness in the early stages of akinetic-rigid syndrome were assessed by functional magnetic resonance imaging (fMRI). Movements of the unaffected hand produced activation in the contralateral sensorimotor cortex (SMC) and ipsilateral SMC and superior parietal lobule (SPL). The affected hand activated the bilateral SMCs, supplementary motor areas, and SPLs. We speculated that the bilateral activation indicated recruitment of a pre-existing bilaterally organized large-scale neural network to perform the motor task.
AB - The motor mechanisms of a patient with unilateral hand clumsiness in the early stages of akinetic-rigid syndrome were assessed by functional magnetic resonance imaging (fMRI). Movements of the unaffected hand produced activation in the contralateral sensorimotor cortex (SMC) and ipsilateral SMC and superior parietal lobule (SPL). The affected hand activated the bilateral SMCs, supplementary motor areas, and SPLs. We speculated that the bilateral activation indicated recruitment of a pre-existing bilaterally organized large-scale neural network to perform the motor task.
KW - Akinetic-rigid syndrome
KW - Compensation
KW - Corticobasal degeneration
KW - Motor
KW - fMRI
UR - http://www.scopus.com/inward/record.url?scp=3543109592&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3543109592&partnerID=8YFLogxK
U2 - 10.1016/j.clineuro.2004.01.001
DO - 10.1016/j.clineuro.2004.01.001
M3 - Article
C2 - 15297009
AN - SCOPUS:3543109592
VL - 106
SP - 330
EP - 334
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
SN - 0303-8467
IS - 4
ER -