A compensatory mechanism in unilateral akinetic-rigid syndrome: An fMRI study

Keiko Kinomoto, Yoshihro Takayama, Mitsunari Abe, Kimihiro Nakamura, Ichiro Akiguchi

Research output: Contribution to journalArticlepeer-review


The motor mechanisms of a patient with unilateral hand clumsiness in the early stages of akinetic-rigid syndrome were assessed by functional magnetic resonance imaging (fMRI). Movements of the unaffected hand produced activation in the contralateral sensorimotor cortex (SMC) and ipsilateral SMC and superior parietal lobule (SPL). The affected hand activated the bilateral SMCs, supplementary motor areas, and SPLs. We speculated that the bilateral activation indicated recruitment of a pre-existing bilaterally organized large-scale neural network to perform the motor task.

Original languageEnglish
Pages (from-to)330-334
Number of pages5
JournalClinical Neurology and Neurosurgery
Issue number4
Publication statusPublished - 2004 Sep 1


  • Akinetic-rigid syndrome
  • Compensation
  • Corticobasal degeneration
  • Motor
  • fMRI

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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