TY - GEN
T1 - A compact-size and ultrasensitive optical biosensor using a double-spiral microresonator
AU - Igarashi, Anh
AU - Shang, Yugang
AU - Kuroiwa, Shigeki
AU - Ohashi, Keishi
AU - Yamada, Hirohito
N1 - Funding Information:
This research has received the financial support of Tohoku University Center for Gender Equality Promotion (TUMUG) Support Project. We want to thank the technical support from Tohoku University Micro System Integration Center (µSIC) and Tohoku University Fundamental Technology Center for the sample fabrication and evaluation.
Publisher Copyright:
© 2022 IEEE.
PY - 2022
Y1 - 2022
N2 - A structure of a double-spiral microresonator is demonstrated for high-sensitive biosensing of a microliter sample volume of biomolecules. The microring resonator has been applied as a highly potential label-free biosensor; however, the sensitivity still needs to be improved due to the restriction of the sensing surface. In this report, a resonator with two Si-based spiral waveguides connected by an S-shaped channel is designed to be positioned in a hundred-micrometer-width fluidic channel. The enhanced sensing surface on the same footprint of the double spiral resonator contributes a high bulk sensitivity of about 1,500 nm/RIU, 10-fold more sensitive than the sensitivity of the microring resonators according to 2D-FDTD simulation results. In addition, the fabricated double spiral resonator shows Q-factors of 14,000 in air and 12,000 in water, which doubles that of the conventional microring. The double-spiral structured microresonator can be further applied with a microfluidic channel for detecting changes in biomolecules in real time.
AB - A structure of a double-spiral microresonator is demonstrated for high-sensitive biosensing of a microliter sample volume of biomolecules. The microring resonator has been applied as a highly potential label-free biosensor; however, the sensitivity still needs to be improved due to the restriction of the sensing surface. In this report, a resonator with two Si-based spiral waveguides connected by an S-shaped channel is designed to be positioned in a hundred-micrometer-width fluidic channel. The enhanced sensing surface on the same footprint of the double spiral resonator contributes a high bulk sensitivity of about 1,500 nm/RIU, 10-fold more sensitive than the sensitivity of the microring resonators according to 2D-FDTD simulation results. In addition, the fabricated double spiral resonator shows Q-factors of 14,000 in air and 12,000 in water, which doubles that of the conventional microring. The double-spiral structured microresonator can be further applied with a microfluidic channel for detecting changes in biomolecules in real time.
KW - Double-spiral
KW - microresonator
KW - sensing surface
UR - http://www.scopus.com/inward/record.url?scp=85144057276&partnerID=8YFLogxK
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U2 - 10.1109/SENSORS52175.2022.9967064
DO - 10.1109/SENSORS52175.2022.9967064
M3 - Conference contribution
AN - SCOPUS:85144057276
T3 - Proceedings of IEEE Sensors
BT - 2022 IEEE Sensors, SENSORS 2022 - Conference Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2022 IEEE Sensors Conference, SENSORS 2022
Y2 - 30 October 2022 through 2 November 2022
ER -