Abstract
A cationic fluorescent nanogel thermometer based on thermo-responsive N-isopropylacrylamide and environment-sensitive benzothiadiazole was developed with a new azo compound bearing imidazolium rings as the first cationic radical initiator. This cationic fluorescent nanogel thermometer showed an excellent ability to enter live mammalian cells in a short incubation period (10 min), a high sensitivity to temperature variations in live cells (temperature resolution of 0.02–0.84 °C in the range 20–40 °C), and remarkable non-cytotoxicity, which permitted ordinary cell proliferation and even differentiation of primary cultured cells.
Original language | English |
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Pages (from-to) | 5413-5417 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 57 |
Issue number | 19 |
DOIs | |
Publication status | Published - 2018 May 4 |
Externally published | Yes |
Keywords
- fluorescence spectroscopy
- fluorescent probes
- imaging agents
- nanoparticles
- sensors
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)