A case report of very late stent thrombosis with peri-stent coronary artery aneurysm and stent-related coronary vasospasm

Morihiko Takeda, Nobuyuki Shiba, Jun Takahashi, Hiroaki Shimokawa

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We describe a 42-year-old man with very late stent thrombosis (VLST) 35 months after implantation of a sirolimus-eluting stent (SES). Three months after the VLST episode, a follow-up angiography showed a formation of peri-stent coronary artery aneurysm. Sixty-five months after SES implantation, the patient suffered an out-of-hospital cardiac arrest. We performed spasm provocation test using acetylcholine to evaluate coronary vasomotor response and the coronary segments adjacent to the SES showed significant vasoconstriction. Intracoronary pretreatment of Rho-kinase inhibitor, fasudil, markedly attenuated acetylcholine-induced vasoconstriction. This report documents a unique case suffering from multiple fatal complications after SES implantation.

Original languageEnglish
Pages (from-to)272-278
Number of pages7
JournalCardiovascular Intervention and Therapeutics
Volume28
Issue number3
DOIs
Publication statusPublished - 2013 Jul

Keywords

  • Coronary artery aneurysm
  • Coronary vasospasm
  • Fasudil
  • Rho-kinase
  • Very late stent thrombosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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