TY - JOUR
T1 - A Case Report of Pancreatic Mucin-producing Cystic Tumor with Carcinoma in Situ of the Dilated Main Pancreatic Duct
AU - Takahashi, Masaru
AU - Usui, Ritsuro
AU - Watanabe, Shinkichi
AU - Miyakawa, Hidenobu
AU - Honda, Tsuyohiko
AU - Abe, Masahide
AU - Furukawa, Touru
PY - 1993
Y1 - 1993
N2 - We report a case of a pancreatic mucin-producing cystic tumor with carcinoma in situ of the dilated main pancreatic duct detected by immunohistological staining. The patient, a 76-year-old man, was admitted for enlargement of pancreaticcysts and elevation of CEA and CA19-9, although small cysts of the tail of the pancreas were found 5 yearsearlier. Distal pancreatectomy was performed because of a strong suspicion of malignancy. Macroscopically, multiple cysts were located in the whole pancreas and communicated with the main pancreatic duct. By histological examination of the whole specimen cut into 1.5 mm sections, the only lesion of dilated main pancreatic duct was diagnosed as carcinoma in situ because of swelling of the nuclei, increase in chromatin, distinct nucleoli and disappearance of cell polarity. The lesion was strongly stained immunohistologically in the apical portion and cytoplasm of cells by CEA.
AB - We report a case of a pancreatic mucin-producing cystic tumor with carcinoma in situ of the dilated main pancreatic duct detected by immunohistological staining. The patient, a 76-year-old man, was admitted for enlargement of pancreaticcysts and elevation of CEA and CA19-9, although small cysts of the tail of the pancreas were found 5 yearsearlier. Distal pancreatectomy was performed because of a strong suspicion of malignancy. Macroscopically, multiple cysts were located in the whole pancreas and communicated with the main pancreatic duct. By histological examination of the whole specimen cut into 1.5 mm sections, the only lesion of dilated main pancreatic duct was diagnosed as carcinoma in situ because of swelling of the nuclei, increase in chromatin, distinct nucleoli and disappearance of cell polarity. The lesion was strongly stained immunohistologically in the apical portion and cytoplasm of cells by CEA.
KW - carcinoma in situ
KW - immunohistological CEA staining
KW - pancreatic mucin-producing cystic tumor
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U2 - 10.5833/jjgs.26.937
DO - 10.5833/jjgs.26.937
M3 - Article
AN - SCOPUS:84996362727
SN - 0386-9768
VL - 26
SP - 937
EP - 941
JO - Japanese Journal of Gastroenterological Surgery
JF - Japanese Journal of Gastroenterological Surgery
IS - 3
ER -