A case report of complete pathological response of a locally advanced rectal cancer after long term chemotherapy

Minoru Kobayashi, Shinobu Ohnuma, Shunsuke Kato, Hideaki Karasawa, Takeshi Aoki, Katsuyoshi Kudo, Naoki Tanaka, Kazuhiro Watanabe, Munenori Nagao, Tomoya Abe, Hiroaki Musha, Takanori Morikawa, Fuyuhiko Motoi, Yu Katayose, Takeshi Naito, Michiaki Unno

Research output: Contribution to journalArticlepeer-review

Abstract

A-39-year-old man presented to a nearby clinic owing to long-term diarrhea and painful defecation. He was diagnosed with a well-differentiated tubular adenocarcinoma of the rectosigmoid and underwent a laparotomy at another hospital. At surgery, the tumor was seen to deeply invade into the urinary bladder with the presence of intra-abdominal abscess. Loop sigmoid colostomy was performed due to possible invasion into the pelvic wall and peritoneal dissemination. The patient was referred to the our hospital for systemic chemotherapy. After 32 courses of FOLFIRI, 10 courses of CapeOX+Bmab, and 34 courses of LV5FU2+Bmab, radiographic examination revealed complete response (CR) of the rectal tumor, and low anterior resection of the rectum was carried out. Since pathological examination showed no viable cancer cells in any specimen, the patient was considered to have achieved a CR from a pathological standpoint.

Original languageEnglish
Pages (from-to)1755-1757
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume41
Issue number12
Publication statusPublished - 2014 Nov

Keywords

  • Complete response
  • Rectal cancer

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'A case report of complete pathological response of a locally advanced rectal cancer after long term chemotherapy'. Together they form a unique fingerprint.

Cite this